TB-HIV
Stimulating and shaping the market for HIV self-testing in Africa: two-tier demonstration and evaluation of accuracy and linkage in 4 countries.
Aims: Stimulate and shape the market for HIV self-testing in Africa using data collection and modelling
People: Liz Corbett, Tom Sumner, Rein Houben, Andrew Philips (UCL), Richard White, and colleagues
Funding: UNITAID
Impact of a conditional cash transfer programme on HIV/AIDS and tuberculosis in Brazil and forecast of effectiveness scenarios
Aims: Estimate the impact of a conditional cash transfer programme on HIV/AIDS and Tuberculosis in Brazil and forecast of effectiveness scenarios
People: Davide Rasella (Wellcome Trust), Rein Houben, Laura Rodrigues, Richard White, and colleagues
Funding: Wellcome Trust
Potential impact of future TB vaccines in high HIV prevalent settings and aging populations
Aims: Estimate the epidemiological impact of potential TB vaccines in high burden settings with high HIV prevalence; Estimate the epidemiological impact of potential TB vaccines in high burden settings with ageing populations; Model outcomes can be used to prioritise development of vaccine candidates with greatest potential public health impact
People: Rebecca Harris, Tom Sumner, Gwen Knight (Imperial), Richard White, and colleagues
Funding: Medical Research Council
Closed projects
Consortium to respond effectively to the AIDS/TB epidemic (CREATE)
Aims: Reduce death and disease from TB in populations with high rates of HIV AIDS; 4 interventions: Zamstar: HH & ECF, Thibela TB: Mass IPT, DetecTB: ACF; Develop models that fit baseline populations; Gather data on key unknowns; Provide timely modelling, projection, and better understanding of trial results; Project longer term impact and alternative strategies
People: Liz Corbett, Richard White, Emilia Vynnycky, Richard Hayes, Dick Chaisson (JHU), Tom Sumner, Emilia Vynnycky, Pete Dodd (Sheffield)
Funding: Bill and Melinda Gates Foundation
Impact of IPT and ART on TB in South Africa
Aims: Provide evidence for policy making on how best to use IPT and ART to control TB in South Africa using mathematical modelling; Use empirical data to create model scenarios representing the diversity of TB/HIV epidemics in South Africa; Simulate range of scenarios of IPT and ART targeting and scale-up to estimate impact on MTB transmission and TB disease incidence; Provide setting-specific policy recommendations
People: Richard White, Emilia Vynnycky, Rein Houben, Katherine Fielding, Alison Grant, Taraz Samandari (CDC), Tom Sumner, Gwen Knight, Pete Dodd (Sheffield)
Funding: CDC/PEPFAR via Aurum Institute